Sleep variables identified as potential biomarkers for early diagnosis of PD

Specialists have identified a number of polysomnographic (PSG) alterations that are already present in prediagnostic Parkinson’s disease (PD), and could be useful as potential early biomarkers.

REM sleep behavior disorder (RBD) has been well investigated as a prodromal PD sleep disorder, but relatively little is known about the association of REM sleep without atonia (RSWA) and other PSG variables with prediagnostic PD.