Periodized exercise for rehabilitation in multiple sclerosis


  • A periodized training regimen for people with multiple sclerosis (MS) achieved greater improvements in exercise capacity compared to conventional exercise with less than half the training time.

Why this matters

  • Reduced exercise capacity is a key secondary symptom of MS and the primary treatment strategy for MS includes a combination of pharmaceutical and exercise-based intervention.

  • It is believed that high-intensity exercise modalities are more effective than conventional low to moderate modalities, but optimization is required to ensure programs have good adherence and are sustainable.

  • Periodizing high-intensity exercise in MS rehabilitation may help to improve outcomes not only in exercise capacity, but in body composition and muscle strength.

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