Identification of two epitope markers which predict multiple sclerosis in optic neuritis patients

Takeaway

  • This pilot study on epitope diagnostics for multiple sclerosis (MS) identifies novel immunological disease features using unbiased mimotope variation analysis (MVA).

Why this matters

  • Optic neuritis (ON) can occur in isolation or develop into MS; however, predictive factors of this progression remain poorly understood, as do the central nervous system (CNS) antigens targeted by T and B cells in MS.

  • The identification of novel disease features highlights the importance of understanding immunoreactivity at the epitope level in MS to aid current and future efforts towards personalized treatment development.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.