Genetic association between glycemic traits, diabetes and cerebrovascular disease

Takeaway

  • Genetic predisposition to type 2 diabetes (T2D) and hyperglycemia are associated with a higher risk of large artery and small vessel ischemic stroke (IS).

Why this matters

  • Mendelian randomization (MR) uses genetic variants as instruments for traits of interest and has proven a powerful method for inferring causality; this may prove useful in determining predisposition for IS by exploring related traits including insulin resistance.

  • Identification of individuals predisposed to higher IS risk may lead to early preventative measures to reduce IS incidence, and consequently both improve patient outcomes and relieve financial burden on healthcare providers.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.