Brain metabolism patterns may predict long-term cognitive performance in Alzheimer’s Disease

Takeaway

  • A pattern of metabolic brain activity determined through FDG-PET scans could provide a cognitive resilience signature that may identify important information in conjunction with other Alzheimer’s disease biomarkers, for the determination of clinical prognosis.

Why this matters ?

  • Determining the neural correlates of cognitive resilience in Alzheimer’s disease will help clarify the clinical significance of the pathology seen by in vivo biomarkers and provide mechanistic insights into the development of alternative therapeutic approaches.